James Spencer may refer to: James B. Spencer (1781–1848), U.S. Representative from New York James C. Spencer (1914–2009), member of the Texas House of Representatives from Henderson County James G. Spencer (1844–1926), U.S. Representative from Mississippi James Spencer (footballer, born 1985), English football player James Spencer (footballer, born 1991), English football player James Spencer (cross-country skier) (born 1936), British Olympic skier James R. Spencer (born 1949), former District Judge of the United States District Court for the Eastern District of Virginia Sir James Ernest Spencer, British Member of Parliament for West Bromwich, 1886–1906 James Spencer, Lord Mayor of London in 1527