Joseph O'Brien may refer to: Joseph O'Brien (jockey) (born 1993), Irish jockey Joseph C. O'Brien (born 1965), mayor of Worcester, Massachusetts, USA Joseph J. O'Brien (1897–1953), U.S. congressman from New York Joseph Leonard O'Brien (1895–1973), Lieutenant Governor of New Brunswick Joe O'Brien (born 1955), basketball player Joe O'Brien (footballer) (1875 – after 1906), Scottish football full back Joey O'Brien (born 1986), Irish international and former Bolton Wanderers footballer