John J. DeSimone (born November 26, 1960 in Providence, Rhode Island) is an American politician, a former Democratic member of the Rhode Island House of Representatives who represented House District 6 from January 1993 until January 2003 and District 5 from January 2003 to January 2017. DeSimone was narrowly defeated in the 2016 Democratic primary by progressive candidate Marcia Ranglin-Vassell, ending his 24 year tenure in the General Assembly.