Signe Asmussen Manuitt (born 1970) is a Danish mezzosoprano singer who has performed widely, not only in classical concerts, chamber music and opera but also in Latin jazz and as a member of the Tolkien Ensemble. Since 2001, she has made a mark as one of Denmark's most impressive female singers. In addition to appearances in Denmark, she has given recitals in London's Wigmore Hall and Amsterdam's Concertgebouw. Asmussen recently starred as Hanna Glawari in Operette Kompagniet's production of The Merry Widow. She is married to the Cuban Salsa singer Ernesto Manuitt.