A comedy that follows the chaos that ensues when a meteor hits the Earth carrying alien life forms that give new meaning to the term "survival of the fittest." David Duchovny, Orlando Jones, Seann William Scott, and Julianne Moore are the only people standing between the aliens and world domination... which could be bad news for the Earth.
A lone-wolf scientist sequestered in a mansion near a small desert town arouses the suspicion of the town's doctor when his lab assistant is found dead from a case of acromegaly which took only four days to develop. As the doctor investigates, aided by the scientist's new, and very female, assistant, they discover that, far worse, something much larger and hungrier than it ever should be, is devouring local cattle - and humans - in increasingly large quantities.