In April of 1945, Germany stands at the brink of defeat with the Russian Army closing in from the east and the Allied Expeditionary Force attacking from the west. In Berlin, capital of the Third Reich, Adolf Hitler proclaims that Germany will still achieve victory and orders his generals and advisers to fight to the last man. When the end finally does come, and Hitler lies dead by his own hand, what is left of his military must find a way to end the killing that is the Battle of Berlin, and lay down their arms in surrender.
Brothers John and Matt have inherited an island cabin from their recently deceased uncle. Along with Matt's girlfriend, Nicki, and other mutual friends, the siblings travel to the cabin for a relaxing weekend getaway. But, not long after arriving, the group is besieged by ravenous dogs. They watch in horror as another vacationer, Luke, is eaten alive. Soon, they discover a training facility where the dogs have been bred to kill.