An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.
Simon is an intelligent and privileged young man whose family expects him to become a Princeton graduate. Crying out for attention from his reserved and cool hearted family, Simon commits numerous petty crimes and is soon sent away to boarding school where he befriends a "Deadhead," adopts the "hippie" lifestyle and dabbles in many drugs in his search for acceptance.
Soon after the rising young singer-songwriter Beau Williams gets involved with a fallen, emotionally unstable country star Kelly Canter, the pair embark on a career resurrection tour helmed by her husband/manager James and featuring a beauty queen-turned-singer Chiles Stanton. Between concerts, romantic entanglements and old demons threaten to derail them all.
In the mid-1960s, wealthy debutant Edie Sedgwick meets artist Andy Warhol. She joins Warhol's famous Factory and becomes his muse. Although she seems to have it all, Edie cannot have the love she craves from Andy, and she has an affair with a charismatic musician, who pushes her to seek independence from the artist and the milieu.
Two women with a passion for motorcycles meet while going through rehab. When they discover they've both longed to ride Captain America's red, white, and blue chopper from Easy Rider, they escape the rehab clinic and hit the highway in search of their dream bike.
Kate and Charlie like to have a good time. Their marriage thrives on a shared fondness for music, laughter… and getting smashed. When Kate’s partying spirals into hard-core asocial behavior, compromising her job as an elementary schoolteacher, something’s got to give. But change isn’t exactly a cakewalk. Sobriety means she will have to confront the lies she’s been spinning at work, her troubling relationship with her mother, and the nature of her bond with Charlie.
A massage therapist looking to overcome her addictions and reconnect with her son, whose father is an anthropologist in South America studying the Yanomani people, moves in with a wealthy ex-client.