Kate Soffel is married to a prison warden in Pittsburgh, and is the mother of their four children. Ed Biddle is a convicted murderer awaiting execution on death row with his brother Jack. When Kate meets Eddie through her Bible readings to the prisoners, she is drawn to him, and they pursue a clandestine relationship. She agrees to help the brothers escape, and begins a treacherous journey with them to freedom in Canada.
To foil a terrorist plot, an FBI agent undergoes facial transplant surgery to assume the identity of the criminal mastermind who murdered his only son, but the criminal wakes up prematurely and seeks revenge.
After working as a drug courier and getting into a brutal shootout with police, a former boxer finds himself at the mercy of his enemies as they force him to instigate violent acts that turn the prison he resides in into a battleground.