Working-class father John Crowley is finally on the fast track to corporate success when his two young children are diagnosed with Pompe disease—a condition that prevents the body from breaking down sugar. With the support of his wife, John ditches his career and teams with unconventional specialist, Dr. Robert Stonehill to found a bio-tech company and develop a cure in time to save the lives of his children. As Dr. Stonehill works tirelessly to prove the theories that made him the black sheep of the medical community, a powerful bond is forged between the two unlikely allies.
Russian terrorists conspire to hijack the aircraft with the president and his family on board. The commander in chief finds himself facing an impossible predicament: give in to the terrorists and sacrifice his family, or risk everything to uphold his principles - and the integrity of the nation.
After the death of their loved ones in a tragic plane crash, Harrison Ford and Kristin Scott Thomas find each other's keys in each other's loved ones' possessions and realize that the two were having an affair and they must figure out all the details.
A sheltered Amish child is the sole witness of a brutal murder in a restroom at a Philadelphia train station, and he must be protected. The assignment falls to a taciturn detective who goes undercover in a Pennsylvania Dutch community. On the farm, he slowly assimilates despite his urban grit and forges a romantic bond with the child's beautiful mother.
An ugly duckling having undergone a remarkable change, still harbors feelings for her crush: a carefree playboy, but not before his business-focused brother has something to say about it.
When Quinn, a grouchy pilot living the good life in the South Pacific, agrees to transfer a savvy fashion editor, Robin, to Tahiti, he ends up stranded on a deserted island with her after their plane crashes. The pair avoid each other at first, until they're forced to team up to escape from the island -- and some pirates who want their heads.
Respected lawyer, Henry Turner survives a convenience-store shooting only to find he has lost his memory, and has serious speech and mobility issues. After also losing his job—where he no longer 'fits in'—his loving wife and daughter give him all their love and support.
Wrongfully convicted of murdering his wife and sentenced to death, Richard Kimble escapes from the law in an attempt to find her killer and clear his name. Pursuing him is a team of U.S. marshals led by Deputy Samuel Gerard, a determined detective who will not rest until Richard is captured. As Kimble leads the marshals through a series of intricate chases, he uncovers the secret behind his wife's death and struggles to expose the killer before he is recaptured, or killed.
Allie Fox, an American inventor exhausted by the perceived danger and degradation of modern society, decides to escape with his wife and children to Belize. In the jungle, he tries with mad determination to create a utopian community with disastrous results.