The story follows Ichigo Momomiya, a girl who transforms into Mew Ichigo (Strawberry) with the power of the Iriomote leopard cat to save Earth from parasitic Chimera Anima aliens.
The story begins when the gods call a convention to decide the whether to let humanity live or die, and settle on destroying humanity. But a lone valkyrie puts forward a suggestion to let the gods and humanity fight one last battle, as a last hope for humanity's continued survival. 13 gods will fight against 13 human champions in one-on-one battles to decide whether humanity lives or dies.
Tai is now a university student, living alone, working hard at school, and working every day, but with his future still undecided. Meanwhile, Matt and others continue to work on Digimon incidents and activities that help people with their partner Digimon. When an unprecedented phenomenon occurs, the DigiDestined discover that when they grow up, their relationship with their partner Digimon will come closer to an end. As a countdown timer activates on the Digivice, they realize that the more they fight with their partner Digimon, the faster their bond breaks. Will they fight for others and lose their partner? The time to choose and decide is approaching fast. There is a short time before “chosen children” will become adults. This is the last adventure of Tai and Agumon.