England, 1021. Rob Cole, a boy born in a miserable mining town, swears to become a physician and vanquish disease and death. His harsh path of many years, a quest for knowledge besieged by countless challenges and sacrifices, leads him to the remote Isfahan, in Persia, where he meets Ibn Sina, the greatest healer of his time.
John, a 35-year-old window cleaner, has dedicated his life to bringing up his 4-year-old son, Michael, after the child's mother left them soon after giving birth. When John is given only a few months left to live, he attempts to find a new, perfect family for Michael, determined to shield him from the terrible reality of the situation.