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Efsun, who works as a dermatologist, lives peacefully on the farm with her father in a village in Gaziantep. Her mother left her and her father at a young age and moved to Istanbul and became one of Turkey's most important plastic surgeons. Efsun suddenly receives news from her mother, whom she has not seen since she was 12 years old. Her mother is on her deathbed and wants to see her one last time. She invites Efsun to Istanbul by sending her driver. Efsun, who goes to Istanbul to see her mother, is in for a big surprise. Her mother, the owner of the largest aesthetic clinic in Istanbul, asks Efsun to work in the clinic and forces her to do so. As if all this is not enough, Emir, who she thinks is a driver, is actually the son of her mother's partner Kaya Bey. Emir, a handsome and charismatic surgeon, thinks that Efsun has come to take the clinic away from him, and starts a fight with Efsun. Moreover, these young people are neighbors
Zeynep who lives with her twin children, is divorced from Oktay whom she married with great love during her university years, because she was cheated on. Zeynep loses her faith in men and closes her heart to love. Until he met Kenan Yelda is one of the women after Kenan and she intends to carry on the business partnership they have just started with Kenan to marriage.
Masumiyet follows the story of Bahar, a married mother of two, whose life changes drastically after her 19-year-old daughter falls in love with a wrong man. Her daughter Ela's first love is not a college student her age, but her father's 35-year-old boss, who is about to marry someone else. Bahar, who is trying to save her daughter from this wrong relationship, can not prevent what will happen, no matter what she does. An event that occurs on the day of Ela's 19th birthday party, changes the lives of Bahar and that of her family forever!
Özgür is a very wealthy restaurant owner and living a sloppy but happy go lucky life, and does not believe in love. Ezgi is now tired of wrong relationships and is determined to have a proper relationship and get married. Seeing that Ezgi is not successful in the relationship matters, Özgür begins to mentor her about relationships and gives her tactics to get the man she likes. Özgür and Ezgi also turns out to be neighbors.