James Durham may refer to: James Durham (baseball) (1881–1949), pitcher in Major League Baseball James R. Durham (1833–1904), Union Army officer and Medal of Honor recipient James J. Durham (1849–1920), Baptist minister in South Carolina and the founder of Morris College Jim Durham (1947–2012), American sportscaster James Derham (1762–1802?), also known as James Durham, the first African American to formally practice medicine in the United States