Charles O'Brien may refer to: Charles O'Brien, 5th Viscount Clare (1673–1706) Charles O'Brien, 6th Viscount Clare (1699–1761), Irish military officer in French service Charles O'Brien, 7th Viscount Clare (1757–1774) Charles O'Brien (colonial administrator) (1859–1935), British Governor of the Seychelles (1912–1918) and Barbados (1918–1925) Charles O'Brien (1882-1968), Scottish Composer Charles O'Brien (cricketer) (1921–1980), Australian cricketer Charles F. X. O'Brien (1879–1940), United States Representative from New Jersey Charles H. O'Brien (1920–2007), State Senator and judge from Tennessee, United States Charles M. O'Brien (1875–1952), Member of the Legislative Assembly of Alberta, Canada (1909–1913) Charles P. O'Brien (born 1939), American research scientist Charlie O'Brien (born 1960), retired American baseball player Charlie O'Brien (racing driver) (born 1955), Australian racing driver