James McGuire may refer to: James Washington Lonoikauoalii McGuire (1862–1941), Hawaiian courtier and dressmaker Deacon McGuire (James Thomas McGuire, 1863–1936), American baseball player James Kennedy McGuire (1868–1923), American politician, mayor of Syracuse, New York James McGuire (Irish politician) (1903–1989), Irish Cumann na nGaedhael politician James McGuire (soccer) (1911–1974), President of the United States Soccer Federation James McGuire (VC) (1827–1862), Irish recipient of the Victoria Cross Jim McGuire (baseball coach), American college baseball coach Jim McGuire (shortstop) (1875–1917), American baseball shortstop Jimmy McGuire, member of the Jeopardy! Clue Crew