In the final months of World War II, 14-year-old Seita and his sister Setsuko are orphaned when their mother is killed during an air raid in Kobe, Japan. After a falling out with their aunt, they move into an abandoned bomb shelter. With no surviving relatives and their emergency rations depleted, Seita and Setsuko struggle to survive.
Evelyn and her oblivious son Ziggy seek out replacements for each other. As Evelyn tries to parent an unassuming teenager at her shelter, Ziggy fumbles through his pursuit of a brilliant young woman at school.
Wiener-Dog tells several stories featuring people who find their life inspired or changed by one particular dachshund, who seems to be spreading a certain kind of comfort and joy. Man’s best friend starts out teaching a young boy some contorted life lessons before being taken in by a compassionate vet tech named Dawn Wiener. Dawn reunites with someone from her past and sets off on a road trip picking up some depressed mariachis along the way. Wiener-Dog then encounters a floundering film professor, as well as an embittered elderly woman and her needy granddaughter—all longing for something more.