Bob and Joanna, both over 40 years old, have a baby with the Down syndrome. Their doctor advises them to give the child away, not to "waste their time" with a kid with a mental deficiency. But the parents decide to keep their son, to allow him a life with dignity and to support him as best as possible. And their devotion bears fruit...
Georges has Down syndrome, living at a mental-institution, Harry is a busy businessman, giving lectures for young aspiring salesmen. He is successful in his business life, but his social life is a disaster since his wife left him and took their two children with her. This weekend his children came by train to meet him, but Harry, working as always, forgot to pick them up. Neither his wife or his children want to see him again and he is driving around on the country roads, anguished and angry. He almost runs over Georges, on the run from the institution since everybody else went home with their parents except him, whose mother is dead. Harry tries to get rid of Georges but he won't leave his new friend. Eventually a special friendship forms between the two of them, a friendship which makes Harry a different person.
In the late 1970s, when a mentally handicapped teenager is abandoned, a gay couple takes him in and becomes the family he's never had. But once the unconventional living arrangement is discovered by authorities, the men must fight the legal system to adopt the child.
A down-on-his-luck crab fisherman embarks on a journey to get a young man with Down syndrome to a professional wrestling school in rural North Carolina and away from the retirement home where he’s lived for the past two and a half years.