Twenty-five years after a streak of brutal murders shocked the quiet town of Woodsboro, a new killer has donned the Ghostface mask and begins targeting a group of teenagers to resurrect secrets from the town’s deadly past.
When a copycat murderer strikes, Detectives Jake Doyle and Mary Kelly seek help from an incarcerated serial killer called the Artist. As Mary delves deep into the Artist's brilliant but twisted psyche, she and Jake get lured into a diabolical game of cat and mouse, racing against time to stay one step ahead of both criminals.
Two years after the terrifying events that occurred in Woodsboro, Sidney is now attending Windsor College in Cincinnati, and Gale Weathers' best selling book on Sidney's life has now been made into a major motion picture. When two college students are killed in a theatre while watching the new film 'Stab', Sidney knows deep down that history is repeating itself.