Successful surgeon Tomas leaves Prague for an operation, meets a young photographer named Tereza, and brings her back with him. Tereza is surprised to learn that Tomas is already having an affair with the bohemian Sabina, but when the Soviet invasion occurs, all three flee to Switzerland. Sabina begins an affair, Tom continues womanizing, and Tereza, disgusted, returns to Czechoslovakia. Realizing his mistake, Tomas decides to chase after her.
Three friends in their mid-20s struggle to navigate their professional and personal lives, colliding head on with the messy, hilarious and dreadful growing pangs of adulthood.
A waitress agrees to accompany an exotic dancer, her put-upon boyfriend, and her mysterious and domineering roommate on a road trip to Florida to seek their fortune at a high-end strip club.
After losing the woman of his dreams, Anderson is convinced he'll never fall in love again. But at the urging of his best friend, he spontaneously proposes to a dissatisfied waitress named Katie and an innocent dare evolves into the kind of love that both have been looking for all along.
After a one night stand with Alex, Isabel realizes that she is pregnant and they decide to get married. However, along with the marriage comes compromise of one's own cultural traditions.
Lola, a Mexican waitress working in Madrid, befriends a 30-year-old suicidal man who has borrowed $1,000,000 to spend on his last day on Earth, knowing he will be killed anyway if he fails to return the money. After meeting Lola, however, he decides that life might be worth living after all.
Six young people spend the morning after a wild club spree trying to piece together their misadventures from the night before, including a trip to the veterinarian hospital, at least one breakup and the unexpected discovery of a mobster's corpse. As the group shares their fragmented memories, some of their stories start to fit together while others just lead to more questions.