Patience Philips (HALLE BERRY) is a woman who just won't stand up for herself - and the world is more than willing to step all over her in return. A meek people-pleaser, she squanders her considerable artistic talent in a thankless job as a graphics designer for behemoth cosmetics company Hedare Beauty, a 'youth and beauty at all costs' conglomerate run by the tyrannical George Hedare (LAMBERT WILSON) and his icy supermodel wife, Laurel (SHARON STONE).
In a fateful turn of events, Patience's quiet life is forever changed when she overhears a conversation revealing that Hedare's too-good-to-be-true new anti-aging product is…too good to be true. Caught in the wrong place at the worst possible time, Patience is murdered to keep Hedare's secret safe.
But all is not lost.
Resurrected by mysterious forces, she awakens…and she doesn't come back alone. Suddenly gifted with strength, agility and ultra-keen senses, she is no longer just Patience - she is also Catwoman, a seductive creature delicately balancing on the dangerously thin line between good and bad.