Hodaka Morishima, a high-school teenage boy who has run away to Tokyo befriends an orphan girl named Hina Amano, who appears to be able to manipulate the weather. Together they have the chance to change the world forever.
The Umbrella Corporation’s deadly T-virus continues to ravage the Earth, transforming the global population into legions of the flesh eating Undead. The human race’s last and only hope, ALICE (Milla Jovovich), awakens in the heart of Umbrella's most clandestine operations facility and unveils more of her mysterious past as she delves further into the complex. Without a safe haven, Alice continues to hunt those responsible for the outbreak; a chase that takes her from Tokyo to New York, Washington, D.C. and Moscow, culminating in a mind-blowing revelation that will force her to rethink everything that she once thought to be true. Aided by newfound allies and familiar friends, Alice must fight to survive long enough to escape a hostile world on the brink of oblivion. The countdown has begun.