Rachel is a food writer at a New York magazine who meets Washington columnist Mark at a wedding and ends up falling in love with him despite her reservations about marriage. They buy a house, have a daughter, and Rachel thinks they are living happily ever after until she discovers that Mark is having an affair while she is waddling around with a second pregnancy.
The newly married Elizabeth arrives with her new husband, the scientist Henry, at a magnificent house. He tells her that she can do there anything she pleases, except to enter a certain closed room.
Ivan Locke has worked hard to craft a good life for himself. Tonight, that life will collapse around him. On the eve of the biggest challenge of his career, Ivan receives a phone call that sets in motion a series of events that will unravel his family, job, and soul.
Joey Boca is the owner of a pizza parlor located in Tacoma, Washington, and has been married to Rosalie for years. Rosalie is horrified to discover that Joey is a womanizer and has been cheating on her for a long time. Based on the true story of Frances and Anthony Toto.
Pete and Debbie are both about to turn 40, their kids hate each other, both of their businesses are failing, they're on the verge of losing their house, and their relationship is threatening to fall apart.
Twenty-eight-year-old Margot is happily married to Lou, a good-natured cookbook author. But when Margot meets Daniel, a handsome artist who lives across the street, their mutual attraction is undeniable.
Kate and Charlie like to have a good time. Their marriage thrives on a shared fondness for music, laughter… and getting smashed. When Kate’s partying spirals into hard-core asocial behavior, compromising her job as an elementary schoolteacher, something’s got to give. But change isn’t exactly a cakewalk. Sobriety means she will have to confront the lies she’s been spinning at work, her troubling relationship with her mother, and the nature of her bond with Charlie.
When astronaut Spencer Armacost returns to Earth after a mission that nearly cost him his life, he decides to take a desk job in order to see his beautiful wife, Jillian, more often. Gradually, Jillian notices that Spencer's personality seems to have changed, but her concerns fade when she discovers that she's pregnant. As Jillian grows closer to becoming a mother, her suspicions about Spencer return. Why does it seem as if he's a different person?
Jose Luis is an executive at his parents underwear factory where his girlfriend Sylvia works on the shop floor. When Sylvia becomes pregnant, Jose Luis promises her that he will marry her, most likely against the wishes of his parents. Jose Luis' mother is determined to break her son's engagement to a girl from a lower-class family, and hires Raul, a potential underwear model and would-be bullfighter to seduce Sylvia.
Barely escaping an avalanche during a family ski vacation in the Alps, a married couple is thrown into disarray as they are forced to reevaluate their lives and how they feel about each other.