Vignettes weaving together the stories of six individuals in the old West at the end of the Civil War. Following the tales of a sharp-shooting songster, a wannabe bank robber, two weary traveling performers, a lone gold prospector, a woman traveling the West to an uncertain future, and a motley crew of strangers undertaking a carriage ride.
In post-Civil War Wyoming, John Ruth is escorting fugitive Daisy to Red Rock where the latter will face justice for murder. They encounter another bounty hunter named Major Marquis Warren and Chris Mannix. A blizzard forces the four to take shelter at a stagecoach passover where they encounter four more strangers. Through betrayal and deception, the eight strangers soon learn that they may not make it to Red Rock after all.