England, 1021. Rob Cole, a boy born in a miserable mining town, swears to become a physician and vanquish disease and death. His harsh path of many years, a quest for knowledge besieged by countless challenges and sacrifices, leads him to the remote Isfahan, in Persia, where he meets Ibn Sina, the greatest healer of his time.
Set during the last days of the Ottoman Empire, a love triangle develops between Mikael, a brilliant medical student, the beautiful and sophisticated artist Ana, and Chris, a renowned American journalist based in Paris.
Student nurses join some doctors to work in a medical station a few hours flying-time from the Mexican town of Catamaco. One of their planes goes down due to an engine malfunction and crashes in the rain forest. This is the story of the attempts to save the lives of the passengers (both nurses and doctors).
Five medical students, obsessed by the mystery of what lies beyond the confines of life, embark on a daring and dangerous experiment: by stopping their hearts for short periods of time, each triggers a near-death experience - giving them a firsthand account of the afterlife. But as their experiments become increasingly dangerous, they are each haunted by the sins of their pasts, brought on by the paranormal consequences of trespassing to the other side.