For Dan Gallagher, life is good. He is on the rise at his New York law firm, is happily married to his wife, Beth, and has a loving daughter. But, after a casual fling with a sultry book editor named Alex, everything changes. Jilted by Dan, Alex becomes unstable, her behavior escalating from aggressive pursuit to obsessive stalking. Dan realizes that his main problem is not hiding his affair, but rather saving himself and his family.
Maria is a student at the university of Essen, Germany, living and working in a gray, unpleasant, and anonymous environment. While she has little problem finding someone for a one night stand, she rebuffs her lovers in such a rude way that they actually don't know what's going on. But what seems to be a negative attitude at first glance is in fact much worse: Maria is suffering from borderline syndrome, a serious psychotic disease that makes her fail to develop a continuous, reliable personality, from her own perspective as well as from the perspective of those she meets. Then one day, she bumps into Jan, a student who falls in love with her without delay. He's awaiting a hard time when he has to learn how hard it is to stay loyal and faithful to a person who, in her own words, "has a different world inside of her head" and who feels that "there is something inside of me that eats me up."
Breezy is a teen-aged hippy with a big heart. After taking a a ride with a man who only wants her for sex, Breezy manages to escape. She runs to hide on a secluded property where stands the home of a middle-aged divorced man, Frank Harmon. Frank reluctantly takes Breezy in only to fall unexpectedly in love with her.
When former cop and current security expert Jim Holland has a one night stand with Amanda after getting in her way roller-blading. That introduction turns out to be a well thought out plan by Amanda and her sister Molly, to obtain security codes. The girls and their cohorts rob his client and stash the loot. All the while, detective Jim has been following them and he grabs the money for himself. Then his conscience gets the best of him and he falls in love with Molly. His client turns out to be drug dealers and he's forced to risk his life to protect Molly and Amanda.
In Los Angeles, Max Carlyle makes a good living directing commercials and has a happy home life with his wife, Mimi, and two children. When Carlyle travels to New York City to visit his friend Charlie, who has been diagnosed with AIDS, he has repeat run-ins with a beautiful woman, Karen, and eventually sleeps with her. Though he goes home the next day and doesn't return until a year later, Carlyle's infidelity still lingers.
A small town waitress gets a nail accidentally lodged in her head causing unpredictable behavior that leads her to Washington, DC. Sparks fly when she meets a clueless young senator who takes up her cause - but what happens when love interferes with what you stand for?