48 hours in the life of a burnt-out paramedic. Once called Father Frank for his efforts to rescue lives, Frank sees the ghosts of those he failed to save around every turn. He has tried everything he can to get fired, calling in sick, delaying taking calls where he might have to face one more victim he couldn't help, yet cannot quit the job on his own.
Jack's lavish, fast-paced lifestyle changes one Christmas night when he stumbles into a grocery store holdup and disarms the gunman. The next morning he wakes up in bed lying next to Kate, his college sweetheart he left in order to pursue his career, and to the horrifying discovery that his former life no longer exists. As he stumbles through this alternate suburban universe, Jack finds himself at a crossroad where he must choose between his high-power career and the woman he loves.
Charlie Lang is a simple, kindhearted New York City cop. When he realizes he has no money to tip waitress Yvonne Biasi, Lang offers her half the winnings of his lottery ticket. Amazingly, the ticket happens to be a winner, in the sum of $4 million. True to his word, Lang proceeds to share the prize money with Biasi, which infuriates his greedy wife, Muriel. Not content with the arrangement, Muriel begins scheming to take all the money.
When guardian angel Seth -- who invisibly watches over the citizens of Los Angeles -- becomes captivated by Maggie, a strong-willed heart surgeon, he ponders trading in his pure, otherworldly existence for a mortal life with his beloved. The couple embarks on a tender but forbidden romance spanning heaven and Earth.
Ben Sanderson, an alcoholic Hollywood screenwriter who lost everything because of his drinking, arrives in Las Vegas to drink himself to death. There, he meets and forms an uneasy friendship and non-interference pact with prostitute Sera.
Graduate student Harry Bailey was once one of the most visible undergraduate activists on campus, but now that he's back studying for his master's, he's trying to fly right. Trouble is, the campus is exploding with various student movements, and Harry's girlfriend, Jan, is caught up in most of them. As Harry gets closer to finishing his degree, he finds his iconoclastic attitude increasingly aligned with the students rather than the faculty.