Mike Vecchio and Susan Henderson are preparing for their upcoming wedding. However, they seem to be the only two people at the wedding that are happy. Mike's brother Richie and his wife Joan are going through a divorce, which is upsetting his overly devout Catholic mother Beatrice. Also, Susan's father is carrying on an affair and her sex starved older sister Wilma is going through her troubles with her husband Johnny. All this is going on while Mike's best friend Jerry is trying to bed the maid of honor, Susan's cousin Brenda.
Mollie is a single working mother who's out to find the perfect father for her child. Her baby, Mikey, prefers James, a cab driver turned babysitter who has what it takes to make them both happy. But Mollie won't even consider James. It's going to take all the tricks a baby can think of to bring them together before it's too late
Set on an island off the coast of New England in the summer of 1965, Moonrise Kingdom tells the story of two twelve-year-olds who fall in love, make a secret pact, and run away together into the wilderness. As various authorities try to hunt them down, a violent storm is brewing off-shore – and the peaceful island community is turned upside down in more ways than anyone can handle.
Mollie and James are together and raising a family, which now consists of an older Mikey and his baby sister, Julie. Tension between the siblings arises, and as well with Mollie and James when Mollie's brother Stuart moves in. Mikey is also learning how to use the toilet for the first time.
Sully is a rascally ne'er-do-well approaching retirement age. While he is pressing a worker's compensation suit for a bad knee, he secretly works for his nemesis, Carl, and flirts with Carl's young wife Toby. Sully's long- forgotten son and family have moved back to town, so Sully faces unfamiliar family responsibilities. Meanwhile, Sully's landlady's banker son plots to push through a new development and evict Sully from his mother's life.
When bachelor Walter Davis (Bruce Willis) is set up with his sister-in-law's pretty cousin, Nadia Gates (Kim Basinger), a seemingly average blind date turns into a chaotic night on the town. Walter's brother, Ted (Phil Hartman), tells him not to let Nadia drink alcohol, but he dismisses the warning, and her behavior gets increasingly wild. Walter and Nadia's numerous incidents are made even worse as her former lover David (John Larroquette) relentlessly follows them around town.
When New York psychiatrist Bill Capa visits Los Angeles to take over his murdered colleague's therapy group, he finds himself embroiled in the thick of a mystery when he bumps into Rose and begins a torrid affair.