Flighty Emily "Jacks" Jackson works for the British edition of Vogue magazine. Rather than pursue a relationship, Jacks regularly hooks up with her devoted ex-boyfriend, James Wildstone, and lives with Peter Simon, a gay screenwriter. When Jacks meets Argentinian photographer's assistant Paolo Sarmiento, she assumes he is gay and tries to bring him and Peter together, unaware that Paolo is straight and in love with her.
His wife having recently died, Thomas Jefferson accepts the post of United States ambassador to pre-revolutionary France, though he finds it difficult to adjust to life in a country where the aristocracy subjugates an increasingly restless peasantry. In Paris, he becomes smitten with cultured artist Maria Cosway, but, when his daughter visits from Virginia accompanied by her attractive slave, Sally Hemings, Jefferson's attentions are diverted.
Some thirty years after Arlis witnesses his father murdering a family, he runs into Kay, who happens to be the family's baby who was spared. Kay and Arlis suspect nothing about each other, but when his father returns, old wounds are reopened.
Aspiring architect Tom Thompson is told by mysterious Ruth Abernathy that his best friend, "Bill," has taken his own life. Except that Tom has never met Bill and neither have his incredulous friends. So when Tom foolishly agrees to give the eulogy at Bill's funeral, it sets him on a collision course with Ruth -- who is revealed to be Bill's oversexed mother -- and Julie DeMarco, the longtime crush Tom hasn't seen since they were teens.
Young Shakespeare is forced to stage his latest comedy, "Romeo and Ethel, the Pirate's Daughter," before it's even written. When a lovely noblewoman auditions for a role, they fall into forbidden love -- and his play finds a new life (and title). As their relationship progresses, Shakespeare's comedy soon transforms into tragedy.
Soon after the rising young singer-songwriter Beau Williams gets involved with a fallen, emotionally unstable country star Kelly Canter, the pair embark on a career resurrection tour helmed by her husband/manager James and featuring a beauty queen-turned-singer Chiles Stanton. Between concerts, romantic entanglements and old demons threaten to derail them all.
Maud Bailey, a brilliant English academic, is researching the life and work of poet Christabel La Motte. Roland Michell is an American scholar in London to study Randolph Henry Ash, now best-known for a collection of poems dedicated to his wife. When Maud and Roland discover a cache of love letters that appear to be from Ash to La Motte, they follow a trail of clues across England, echoing the journey of the couple over a century earlier.