Nasty Baby centers around a Brooklyn couple, Freddy and his boyfriend Mo, who are trying to have a baby with the help of their best friend, Polly. Freddy is an artist, and his latest work is all about babies – it’s clear he’s dying to be a father. Polly is a family practitioner who is more interested in having a baby than having a man. Mo is hesitant about the entire idea, especially when Polly isn’t having success with Freddyʼs sperm and the donor responsibility shifts to him. Set almost entirely in the multicultural vibrancy of Fort Greene, Brooklyn, the trio navigates the idea of creating life, when they are confronted by unexpected harassment from particularly aggressive neighborhood man, nicknamed The Bishop. The Bishop is bothersome in small, yet persistent ways, with a hint of danger. As their clashes become increasingly aggressive, someone is bound to get hurt.
Harry (Brian Petsos) is having a very, very bad day. He returns home from an all-night drinking binge with his cousin Cecil (Oscar Issac), to discover that his little dog Jolly...Harry's one true love and the source of light in his dark, solitary life-has been murdered. Brokenhearted and beyond consolation, he vows to track down the dog's murderer at any cost. Armed with a stockpile of firepower in the trunk of his car, he and Cecil embark on a frenzied, alcohol-fueled wild-goose chase, leaving a bloody path of destruction in their wake.
Ex-special operative MacGruber (Forte) is called back into action to take down his archenemy, Dieter Von Cunth (Kilmer), who's in possession of a nuclear warhead and bent on destroying Washington, DC.
When rock star Kent Ramsey kills himself, his friends, family members and bandmates gather together to deal with issues old and new ... and play a few rounds of golf.
Kate and Charlie like to have a good time. Their marriage thrives on a shared fondness for music, laughter… and getting smashed. When Kate’s partying spirals into hard-core asocial behavior, compromising her job as an elementary schoolteacher, something’s got to give. But change isn’t exactly a cakewalk. Sobriety means she will have to confront the lies she’s been spinning at work, her troubling relationship with her mother, and the nature of her bond with Charlie.
Best pals Jason and Daniel indulge in casual flings and revel in their carefree, unattached lives. After learning that the marriage of their friend Mikey is over, they gladly welcome him back into their circle. The three young men make a pact to have fun and avoid commitment. However, when all three find themselves involved in serious relationships, they must keep their romances secret from one another.
Wallace, who is burned out from a string of failed relationships, forms an instant bond with Chantry, who lives with her longtime boyfriend. Together, they puzzle out what it means if your best friend is also the love of your life.
For Charles, video-games are a much needed escape from reality. But when virtual vixen Sophia leads him on a mysterious quest through the lovelorn lives of six New Yorkers, they will all learn that in the game of life...every heart is a moving target.