Countless wiseguy films are spoofed in this film that centers on the neuroses and angst of a powerful Mafia racketeer who suffers from panic attacks. When Paul Vitti needs help dealing with his role in the "family," unlucky shrink Dr. Ben Sobel is given just days to resolve Vitti's emotional crisis and turn him into a happy, well-adjusted gangster.
An ultraconservative police officer suffers a debilitating stroke and is assigned to a rehabilitative program that includes singing lessons - with the drag queen next door.
Wayne Dobie is a shy cop whose low-key demeanor has earned him the affectionate nickname "Mad Dog." After Mad Dog saves the life of Frank Milo, a crime boss and aspiring stand-up comedian, he's offered the company of an attractive young waitress named Glory for a week. At first both are uneasy about the arrangement, but they eventually fall in love. However, the situation becomes complicated when Milo demands Glory back.
Aspiring comic Rupert Pupkin attempts to achieve success in show business by stalking his idol, a late night talk-show host who craves his own privacy.
Since she was a child, Natalie Miller has always thought she was an ugly ducking. Despite her mother's encouragement that she will grow up to be pretty, Natalie has never believed it will happen. She rents a Greenwich Village apartment from an eccentric landlady and gets a job at the Topless Bottom Club. She rides a motorcycle to work, decorates her loft with a moose head, and rides up and down a dumbwaiter to get to her apartment. There Natalie meets David an artist, and the two have a love affair before she discovers he is married.
Gigli is ordered to kidnap the psychologically challenged younger brother of a powerful federal prosecutor. When plans go awry, Gigli's boss sends in Ricki, a gorgeous free-spirited female gangster who has her own set of orders to assist with the kidnapping. But Gigli begins falling for the decidedly unavailable Ricki, which could be a hazard to his occupation.
The comic strip detective finds his life vastly complicated when Breathless Mahoney makes advances towards him while he is trying to battle Big Boy Caprice's united mob.
Following a breakdown and suicide attempt, an aging actor becomes involved with a much younger woman but soon finds that it's difficult to keep pace with her.