To foil a terrorist plot, an FBI agent undergoes facial transplant surgery to assume the identity of the criminal mastermind who murdered his only son, but the criminal wakes up prematurely and seeks revenge.
Hired assassin John Lee is asked by Chinatown crime boss Terence Wei to murder the young son of policeman Stan Zedkov. Lee has the boy in his sights, but his conscience gets the better of him, and he spares the child's life. Afraid that Wei will take revenge on his family in China, Lee seeks out expert forger Meg Coburn to obtain the passport he needs to get out of the country, but a band of replacement killers is soon on his trail.
An antiterrorism agent goes under the knife to acquire the likeness of a terrorist and gather details about a bombing plot. When the terrorist escapes custody, he undergoes surgery to look like the agent so he can get close to the agent's family.