1983 - A young biologist returns home from studies abroad, and feels something wrong with his body. This is the start of the AIDS crisis when the first wave of the epidemic hit Brazil. Lives will change, friends lost and the future uncertain.
Rio de Janeiro, Brazil, 1950. In the conservative home of the Gusmão family, Eurídice and Guida are two inseparable sisters who support each other. While Guida can share with her younger sister the details of her romantic adventures, Eurídice finds in her older sister the encouragement she needs to pursue her dream of becoming a professional pianist.