A deadly virus has spread across the globe. Contagion is everywhere, no one is safe, and no one can be trusted. Four friends race through the back roads of the American West on their way to a secluded utopian beach in the Gulf of Mexico where they could peacefully wait out the pandemic. Their plans take a grim turn when their car breaks down on an isolated road starting a chain of events that will seal their fates.
In the summer of 1987, a college graduate takes a 'nowhere' job at his local amusement park, only to find it's the perfect course to get him prepared for the real world.
Joel is stunned to discover that hs girlfriend Clementine has had her memories of their tumultous relationship erased. Out of desperation, he contracts the inventor of the process, Dr. Howard Mierzwaik, to have Clementine removed from his own memory. But as Joel's memories progressively disappear, he begins to rediscover their earlier passion. From deep within the recesses of his brain, Joel attempts to escape the procedure. As Dr. Mierzwiak and his crew chase him through the maze of his memories, it's clear that Joel just can't get her out of his head. So he starts smuggling her away into parts of his memory where she doesn't belong which alters other things about his memories as well…