Totsuko is a high school student with the ability to see the 'colors' of others. Colors of bliss, excitement, and serenity, plus a color she treasures as her favorite. Kimi, a classmate at her school, gives off the most beautiful color of all. Although she doesn't play an instrument, Totsuko forms a band with Kimi and Rui, a quiet music enthusiast they meet at a used bookstore in a far corner of town. As they practice at an old church on a remote island, music brings them together, forming friendships and stirring affections.
The son of a sailor, 5-year-old Sosuke, lives a quiet life on an oceanside cliff with his mother Lisa. One fateful day, he finds a beautiful goldfish trapped in a bottle on the beach and upon rescuing her, names her Ponyo. But she is no ordinary goldfish.