A rare mutation has occurred within the vampire community - The Reaper. A vampire so consumed with an insatiable bloodlust that they prey on vampires as well as humans, transforming victims who are unlucky enough to survive into Reapers themselves. Blade is asked by the Vampire Nation for his help in preventing a nightmare plague that would wipe out both humans and vampires.
The storyline for the third film finds Blade joining forces with two vampire hunters, part of a group called the Nightstalkers, as they tackle the powerful and ruthless villain Danica Talos. After harvesting the superior blood of the ancestor of all modern vampires, Talos has resurrected the man now known as "Drake" (notice the modernization of the Dracula name) from a century-long sleep in the hopes of finally getting world control for all vampires. Blade, along with the Nightstalkers must unleash a virus that will kill all vamps -- but only are given one chance to make it work.
Starring: Wesley Snipes, Kris Kristopherson, Jessica Biel, Dominic Purcell
In a world where vampires walk the earth, Blade has a goal. His goal is to rid the world of all vampire evil. When Blade witnesses a vampire bite Dr. Karen Jenson, he fights away the beast and takes Jenson back to his hideout. Here, alongside Abraham Whistler, Blade attempts to help heal Jenson. The vampire Quinn who was attacked by Blade, reports back to his master Deacon Frost, who is planning a huge surprise for the human population.