A con-artist meets a tough fighter and sees him as her ticket to a better life. The two make an agreement and head off to New Orleans to arrange a match with "the man" - the mysterious king of bare-knuckled boxing. There are no rules for this fight...one man wins when the other dies.
Santos attempts to lead a people's revolt in Colombia to overthrow the Presidente. When his revolt fails and he is killed, his sister Christina goes to New York to find McBain, a lieutenant Santos rescued during the Vietnam War. McBain agrees to help, recruits his old war buddies, raises some cash by killing a few drug dealers, then leads an attack to topple the Colombian government.