Karla, a young medical student, is trying to cure her brother, Blake, from a terminal sleep illness called Fatal Familial Insomnia, where you are unable to sleep until you die. On her quest to treat him, a more sinister reason for his condition is revealed.
Young police officer Shane Cooper's first day on duty, after relocating to the small town of Red Hill, rapidly turns into a nightmare. News of a prison break, involving convicted murderer Jimmy Conway, sends the local law enforcement officers - led by the town's ruling presence, Old Bill - into a panic and leads to a terrifying and bloody confrontation.